In partial fulfillment of my doctoral degree, I will be presenting my work on “Genomic complexities in the legume-rhizobial symbiosis.” My work is primarily computational and the work is generalizable to many different systems. Open to the public. I will be presenting my work on Thursday, May 31 @ Noon @ the BioSciences building room 257 in St Paul,… Read More »
Last December Google Brain released DeepVariant, a machine-learning based variant caller using convolutional neural networks. While PacBio and Nanopore (long-read) sequencing become more mainstream, there exist massive amounts of data from 2nd generation sequencing* for populations which still have lots of use. For the Medicago HapMap project, we have 262 accessions with various depth of 2nd generation sequencing.… Read More »
Select and resequence reveals relative fitness of bacteria in symbiotic and free-living environments. Abstract Assays to accurately estimate relative fitness of bacteria growing in multistrain communities can advance our understanding of how selection shapes diversity within a lineage. Here, we present a variant of the “evolve and resequence” approach both to estimate relative fitness and to identify genetic… Read More »
